HSV-1 & HSV-2

Science

Herpes simplex viruses 1 and 2 also known as Human Herpes Virus 1 and 2 are member of Herpesviridae and the subfamily of the Alphaherpesvirinae. Both these viruses are common and present in 40-90% and 10 to 60 % of the global population respectively. In the United states 48 percent and 12 percent are believed to have HSV-1 and HSV-2 respectively. Since it is transmitted through an intimate contact , it is also categorized under sexually transmitted infections.

Herpes Simples Virus type 1 is transmitted through oral secretions or sores present on the skin. The infection can be spread through kissing, sharing of toothbrushes, or eating utensils. The HSV -2 on the other hand is spread from one person to another through sexual contact with someone who has a genital HSV-2 infection. It is important to note that both these infections can be spread even if sores are not present. The virus can go through periods of dormancy and outbreaks. HSV-1 tropism drives the virus into mucosal epithelial cells, mainly oro-facial tract, and neurons. HSV-2 infects muco epithelia as well but with a focus on the genital tract and neurons as well.

Transmission

Transmission

The symptoms of HSV typically appear as a single blister or as multiple blisters around the infected areas which is usually mouth, genitals, or rectum. The blisters break later leaving tender sores.

Symptoms

Symptoms

Infectolab Americas HSV-1 & HSV-2 Spot helps to monitor the antigen specific T-cell activity. These cells are part of the adaptive immune system; tracking their immune response gives a clear picture of the stage of the disease as well as providing the tools necessary to assess the success of any treatment. 

Testing

Testing

Though there is no cure for the herpes, treatment can help to relieve the symptoms and pain. Drugs like Famvir, Zovirax and Valtrex are most used drugs to treat the symptoms of Herpes. Warm bath can also relieve the pain associated with genital sores.

Treatment

Treatment

Image by Julia Koblitz

Available Tests for HSV-1 & HSV-2

HSV-1 & HSV-2 ELISPOT

2 ACD Tubes (Yellow top)

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